THE UNIVERSITY OF WESTERN AUSTRALIA
FACULTY OF MEDICINE AND DENTISTRY

YEAR  2000

Agus C, Ilett KF, Kadlubar FF and Minchin RF
Characterization of an ATP-dependent pathway of activation for the heterocyclic amine
carcinogen N-hydroxy-2-amino-3-methylimidazo[44,5-f]quinoline
Carcinogenesis, vol 21, no 6:1213-1219

Ajouz B, Berrier C, Besnard M, Martinac B and Ghazi A
Contributions of the Different Extramembranous Domains of the Mechanosensitive Ion
Channel MscL to Its Response to Membrane Tension
The Journal of Biological Chemistry, Vol 275, No 2: 1015-1022

Blitvich BJ, Ward BK, Frost FA, Ingram DM, Byrne MJ and Ratajczak T
Use of fine-needle aspirates for the identification of mutations within the estrogen receptor ?
hormone-binding domain in tamoxifen-resistant human breast carcinomas
Experimental Oncology, 22: 38-43

Butcher NJ, Ilett KF and Minchin RF
Substrate-Dependent Regulation of Human Arylamine N-Acetyltransferase-1 in Cultured Cells
Molecular Pharmacology, 57: 468-473

Butcher NJ, Ilett KF and Minchin RF
Inactivation of Human Arylamine N-Acetyltransferase 1 by the Hydroxylamine of p Aminobenzoic
Acid
Biochemical Pharmacology, Vol 60: 1829-1836

Coleman NA, Power BM and van Heerden PV
The Use of End-Tidal Carbon Dioxide Monitoring to Confirm Intratracheal Cannula Placement
Prior to Percutaneous Dilatational Tracheostomy
Anaesthetics and Intensive Care, 28: 191-192

Davis TME, Daly F, Walsh JP, Ilett KF, Beilby JP, Dusci LJ and Barrett PHR
Pharmacokinetics and pharmacodynamics of gliclazide in Caucasians and Australian Aborigines
with type 2 diabetes
British Journal of Clinical Pharmacology, 49: 223-230

Djano W and Martin-Iverson MT
Does locomotor response to novelty in rats predict susceptibility to develop sensitisation to
cocaine and PHNO?
Behavioural Pharmacology, 11: 455-470

Glendenning P, Ratajczak T, Prince RL, Garamszegi N and Strehler EE
The Promoter Region of the Human PMCA1 Gene Mediates Transcriptional Downregulation
by 1,25 Dihydroxyvitamin D3
Biochemical and Biophysical Research Communications. 277: 722-728

Goldie RG, D’Aprile AF, Self GJ, Rigby PJ and Henry PJ
Influence of Endothelin-1(1-31) on Smooth Muscle Tone and Cholinergic Nerve-Mediated
Contraction in Rat Isolated Trachea
Journal of Cardiovascular Pharmacology, 36 (Suppl 1): S228-S231

Goldie RG and Fernandes LB
A possible mediator role for endothelin-1 in respiratory disease
Monaldi Archives for Chest Disease, 55: 2, 162-167

Habre W, Bergesio R, Johnson C, Hackett LP, Joyce DA and Sims C
Pharmacokinetics of ropivacaine following caudal analgesia in children
Paediatric Anaesthesia, 10: 143-147

Hansen TG, Ilett KF, Lim SI, Reid C, Hackett LP and Bergesio R
Pharmacokinetics and clinical efficacy of long-term epidural ropivacaine infusion in children
British Journal of Anaesthesia, 85 (3): 347-353

Ilett KF, Johnson S, Greenhill G, Mullen L, Brockis J, Golledge CL and Reid DB
Modification of general practitioner prescribing of antibiotics by use of a therapeutics adviser
(academic detailer)
British Journal of Clinical Pharmacology, 49: 168-173

Ilett KF, McCormick N, Carpenter DS, Spargo RM, Le Souef PN, Musk AW and Minchin RF
Genetic polymorphisms in glutathione S-transferase M1 and T1 in an Australian Aborigine
population
Pharmacogenetics, 10: 477-480

Inglis TJJ, Rigby P, Robertson, TA, Dutton NS, Henderson M and Chang BJ
Interaction between Burkholderia pseudomallei and Acanthamoeba species results in
coiling phagocytosis, endamebic bacterial survival, and escape
Infection and Immunity. March 2000, 1681-1686

Knight DA, D’Aprile, Spalding LJ, Goldie RG and Thompson PJ
Leukaemia inhibitory factor (LIF) upregulates excitatory non-adrenergic non cholinergic and
maintains cholinergic neural function in tracheal explants
British Journal of Pharmacology, 130: 975-979

Kristensen JH and Ilett KF
Drug Therapy and Breastfeeding
Current Therapeutics, April 2000: 53-59

Kroeger KM, Steer JH, Joyce DA and Abraham LJ
Effects of stimulus and cell type on the expression of the –308 Tumour Necrosis Factor
polymorphism
Cytokine, 12: 110-119

Lan RS, Stewart GA and Henry PJ
Modulation of airway smooth muscle tone by protease activated receptor-1, -2, -3 and 4 in
trachea isolated from influenza A virus-infected mice
British Journal of Pharmacology, 129: 63-70

Martin-Iverson MT and Else D
PHNO, a selective dopamine D2 receptor agonist, does not reduce prepulse inhibition of the
startle reflex in rats
Psychopharmacology, 151: 38-48

Minchin RF, Carpenter DS and Orr RJ
Polyinosinic acid and polycationic lipids attenuate the hepatic clearance of circulating plasmid
DNA
Journal of Pharmacology and Experimental Therapeutics. 296: 1006-1012

Munro JD and Martin-Iverson MT
Melatonin effects on the circadian rhythm-dependent development of tolerance to a selective
dopamine D2 receptor agonist in rats
Pharmacology Biochemistry and Behavior, 65(3): 495-501

Oakley AJ and Wilce MCJ
Macromolecular crystallography as a tool for investigating drug, enzyme and receptor
interactions
Clinical and Experimental Pharmacology and Physiology, 27, 145-151
Preuss JMH, Rigby PJ and Goldie RG
Ageing and epithelial integrity as modulators of airway smooth muscle responsiveness to
endothelin-1
Naunyn-Schmiedeberg’s Archives of Pharmacology, 361: 391-396

Rampono J, Kristensen JH, Hackett LP, Paech M, Kohan R and Ilett KF
Citalopram and demethylcitalopram in human milk; distribution, excretion and effects in
breast fed infants
British Journal of Clinical Pharmacology, 50: 263-268

Rodgers AJW and Wilce MCJW
Structure of the ?-? complex of APT synthase
Nature Structural Biology. Vol 7, number 11, November 2000

Ruzich M and Martin-Iverson MT
Pinealectomy blocks stress-induced motor stimulation but not sensitisation and tolerance
to a dopamine D2 receptor agonist
Psychopharmacology, 152: 275-282

Sim E, Payton M, Noble M and Minchin RF
An update on genetic, structural and functional studies of arylamine N-acetyltransferases
in eucaryotes and procaryotes
Human Molecular Genetics. 9: 2435-2441

Steer JH, Kroeger KM, Abraham LJ and Joyce DA
Glucocorticoids Suppress TND-? Expression by Human Monocytic THP-1 Cells by Suppressing
Transactivation Through Adjacent NF-?B and c-Jun/ATF-2 Binding Sites in the Promoter
Journal of Biological Chemistry, 275: 18432-18440

Stewart Z, Martinac B and Dobson J
Evidence for mechanosensitive transmembrane ion channels of small conductance in
magnetotactic bacteria
Electro- and Magnetobiology, 19 (1): 81-89

Tait R, Martin-Iverson MT, Michie P and Dusci LJ
The effects of cigarette consumption on the Sternberg Memory Search Paradigm
Addiction, 95 (3): 437-446

van Heerden PV, Barden A, Michalopoulos N, Bulsara MK and Roberts BL
Dose-Response to Inhaled Aerolosolized Prostacyclin for Hypoxemia Due to ARDS
Chest, 117, 3: 819-827

van Heerden PV, Caterina P, Filion P, Spagnolo DV and Gibbs NM
Pulmonary Toxicity of Inhaled Aerosolized Prostacyclin Therapy – An Observational Study
Anaesthesia and Intensive Care, Vol 28, No 2: 161-166

van Heerden PV, Baker S, Lim SI, Weidman C and Bulsara M
Clinical Evaluation of the Non-Invasive Cardiac Output (NICO) Monitor in the Intensive
Care Unit
Anaesthesia and Intensive Care, Vol 28, No 4: 427-430

van Heerden PV
Simple apparatus for continuous nebulisation of prostacyclin
Anaesthesia, 55: 820-821

Ward BK, Kumar P, Turbett GR, Edmondston JE, Papadimitriou JM, Laing NG, Ingram DM,
Minchin RF and Ratajczak
Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilins, in breast cancer
Journal of Cancer Research and Clinical Oncology. 127: 109-115

Yapp P, Ilett KF, Kristensen JH, Hackett LP, Paech MJ and Rampono J
Drowsiness and Poor Feeding in a Breast-Fed Infant: Association with Nefazodone and
Its Metabolites
The Annals of Pharmacotherapy, November, Vol 34: 1269-1271

Zahler MH, Irani A, Malhi H, Reutens AT, Albanese C, Bouzahzah B, Joyce DA, Gupta S and
Pestell RG
The application of a lentiviral vector for gene transfer in fetal human hepatocytes
Journal of Gene Medicine, 2: 186-193

LETTER

Davis TME and Ilett KF
Relapsing vivax malaria, chloroquine toxicity, anxiety or alcohol misuse
The Annals of Pharmacotherapy, May, Vol 34, 667-668

Hill RC, McIvor RJ, Wojnar-Horton RE, Hackett LP and Ilett KF
Update on “Open Study of the Catechol-O-Methyltransferase Inhibitor Tolcapone in
Major Depressive Disorder”
Journal of Clinical Psychopharmacology, Vol 20, No 2 April, 285-286

ABSTRACT

Fernandes LB, D’Aprile AC and Goldie RG
Respiratory syncytial virus infection in sheep bronchial explants is associated with enhanced
ETB receptor-mediated contractile function
Joint meeting of the Australasian Society of Clinical and Experimental Pharmacologists and
Toxicologists and British Pharmacological Society, Melbourne, Australia, 25-28 April
Proceedings of Australian Society of Clinical and Experimental Pharmacologists and
Toxicologists,7: 129

Goldie RG, Fernandes LB and D’Aprile AC
Respiratory syncytial virus infection in sheep bronchial explants is associated with enhanced
ETB receptor-medicated contraction
World Congress on Lung Health and European Respiratory Society, Florence, Italy 30
August 3 September

van Heerden PV, Baker S, Lim SI, Weidman C and Bulsara M
Clinical evaluation of the non-invasive cardiac output (nico) monitor in the intensive care unit
Combined Congress Critical Care Society of Southern Africa and South African Pulmonary Society.
Durban, South Africa, 23-27 July 2000

van Heerden PV
Selective pulmonary Vasodilators in Acute Lung Injury
Combined Congress Critical Care Society of Southern Africa and South African Pulmonary Society.
Durban, South Africa, 23-27 July 2000

van Heerden PV, Solomon M, Woods WPD and Roberts BL
Medical Futility
Combined Congress Critical Care Society of Southern Africa and South African Pulmonary Society.
Durban, South Africa, 23-27 July 2000

Leonard RL, Lewis R and van Heerden PV
Long-term follow-up of critical care patients who had undergone percutaneous dilational
tracheostomy using the portex kit
Combined Congress Critical Care Society of Southern Africa and South African Pulmonary Society.
Durban, South Africa, 23-27 July 2000

van Heerden PV
Treatment of acute right ventricular failure
Australian Society of Anaesthetists National Conference. Perth, Australia,